炎症中的激肽系统。

The kinin system in inflammation.

作者信息

Stewart J M

机构信息

University of Colorado School of Medicine, Department of Biochemistry, Denver 80262.

出版信息

Agents Actions Suppl. 1993;42:145-57. doi: 10.1007/978-3-0348-7397-0_12.

DOI:10.1007/978-3-0348-7397-0_12

PMID:8356920

Abstract

Bradykinin and related kinins are important mediators of most kinds of inflammation. Mechanisms of kinin production in injury, infection and immune system activation are discussed. Bradykinin antagonists show great promise for development of new drugs for inflammation.

摘要

缓激肽及相关激肽是大多数炎症的重要介质。本文讨论了损伤、感染及免疫系统激活过程中激肽的产生机制。缓激肽拮抗剂在开发新型抗炎药物方面展现出了巨大潜力。