Lalla J K, Shah M U, Jain M B, Sharma A H
Principal K.M. Kundnani College of Pharmacy, Bombay, India.
J Pharm Biomed Anal. 1993 Apr-May;11(4-5):385-8. doi: 10.1016/0731-7085(93)80033-w.
An HPLC method is described for the determination of drotaverine in plasma; papaverine is used as the internal standard. The lower limit of quantitation is 50 ng ml-1 with an inter-assay precision (RSD) of below 4%. The method has been validated and successfully used to assay clinical trial samples in healthy volunteers.
描述了一种用于测定血浆中屈他维林的高效液相色谱法；罂粟碱用作内标。定量下限为50 ng/ml，批间精密度（相对标准偏差）低于4%。该方法已得到验证，并成功用于检测健康志愿者的临床试验样本。
