从感染茄病镰刀菌的甘薯（Ipomea batatas）中分离出的呋喃萜类化合物对肺的损伤
Lung injury by furanoterpenoids isolated from Fusarium solani infected sweet potato, Ipomea batatas.
作者信息
Parasakthy K, Shanthi S, Devaraj S N
机构信息
Department of Biochemistry, University of Madras, India.
出版信息
Indian J Exp Biol. 1993 Apr;31(4):397-8.
PMID:8359843
Abstract
Intraperitoneal administration (1 mg/kg body/wt./day for 21 days) of crude extract of furanoterpenoids, isolated from F. solani damaged I. batatas caused pulmonary oedema in albino rats. The elevated broncho alveolar lavage (BAL) angiotensin converting enzyme (ACE), lactate dehydrogenase (LDH) and protein levels indicated lung damage. The estimation of pulmonary extracellular surfactant phospholipids showed an alteration in various phospholipid fractions.
摘要
腹腔注射（1毫克/千克体重/天，共21天）从茄病镰刀菌损伤的甘薯中分离得到的呋喃萜类粗提物，可导致白化大鼠出现肺水肿。支气管肺泡灌洗（BAL）中血管紧张素转换酶（ACE）、乳酸脱氢酶（LDH）和蛋白质水平升高表明肺部受损。肺细胞外表面活性物质磷脂的测定显示各种磷脂组分发生了改变。
Zotero 插件