Leung S F, Teo P M, Foo W W, Van Hasselt C A, Shiu W C, Ting C L, Lau J T
Department of Clinical Oncology, Prince of Wales Hospital, Shatin, Hong Kong.
Head Neck. 1993 Jul-Aug;15(4):296-9. doi: 10.1002/hed.2880150405.
Pretreatment neck node biopsy had been performed on 50 of 422 patients who had cervical node metastases from nasopharyngeal carcinoma when initially seen. Multivariate analysis using the Cox proportional hazards model shows that pretreatment node biopsy is not a significant determinant of distant metastases, survival, or recurrence in the neck. Results of similar studies are reviewed and the role of pretreatment node biopsy in nasopharyngeal carcinoma discussed.
422例初诊时已有鼻咽癌颈部淋巴结转移的患者中,50例进行了治疗前颈部淋巴结活检。采用Cox比例风险模型进行多因素分析显示,治疗前淋巴结活检并非远处转移、生存或颈部复发的显著决定因素。本文回顾了类似研究的结果,并讨论了治疗前淋巴结活检在鼻咽癌中的作用。