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脑库与非神经组织。

Brain banks and non nervous tissues.

作者信息

Palacin A, Cardozo A, Cardesa A, Cruz-Sanchez F F

机构信息

Department of Pathology, Hospital Clinico, University of Barcelona, Spain.

出版信息

J Neural Transm Suppl. 1993;39:87-96.

PMID:8360668
Abstract

Nervous system diseases may not be confined to neural tissue, but also affect other organs. These organs could be involved indirectly or could be simultaneously affected by the same pathological process. A brain bank (BB) should also guarantee the storage of specific organs primarily or secondary affected other than nervous system. Tissues from patients with primary nervous system diseases without or with unknown systemic involvement should also be stored. Samples stored will be identified and registered in a BB database for an accurate distribution and utilization of the material. To guarantee the best quality of the material stored, several techniques for the collection and preservation (cryopreservation, chemical fixation and microwave irradiation) and tissue management are described.

摘要

神经系统疾病可能不仅局限于神经组织,还会影响其他器官。这些器官可能会受到间接影响,或者可能同时受到相同病理过程的影响。脑库(BB)还应确保存储除神经系统外主要或次要受影响的特定器官。患有原发性神经系统疾病且无或有未知全身受累的患者的组织也应予以存储。所存储的样本将在脑库数据库中进行识别和登记,以便对材料进行准确分发和利用。为确保所存储材料的最佳质量,本文描述了几种采集和保存(冷冻保存、化学固定和微波辐照)及组织管理技术。

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