Pfenninger J, D'Apuzzo V
Arch Dis Child. 1977 Feb;52(2):157-9. doi: 10.1136/adc.52.2.157.
Two cases of powder aspiration are reported. A 7 1/2-month-old girl showed a classical course with an asymptomatic period of 3-4 hours, then severe respiratory distress developed. Acute respiratory insufficiency made tracheal intubation and mechanical ventilation necessary for 10 days. Complications included insufficient alveolar ventilation, atelectasis, pneumothorax, and superinfection. But the baby recovered with some residual radiological changes in the lungs. A 13-month-old boy was treated immediately after massive powder aspiration by tracheal intubation and bronchial wash-out. The postoperative course was unevetful and no respiratory distress developed. Powder aspiration leads to severe bronchiolar obstruction with a delay of several hours and has a high mortality rate. The best results in treatment are obtained by immediate intubation and bronchial wash-out, even in the absence of respiratory symptoms. Artifical ventilation may be necessary with the special problem of overcoming very high airway resistance. Corticosteroids and bronchodilators may be helpful.
报告了两例吸入粉末的病例。一名7个半月大的女孩呈现出典型病程,有3 - 4小时的无症状期,随后出现严重呼吸窘迫。急性呼吸功能不全使得气管插管和机械通气持续了10天。并发症包括肺泡通气不足、肺不张、气胸和继发感染。但婴儿康复后肺部仍有一些残留的影像学改变。一名13个月大的男孩在大量吸入粉末后立即接受了气管插管和支气管冲洗治疗。术后病程平稳,未出现呼吸窘迫。吸入粉末会导致严重的细支气管阻塞,延迟数小时,且死亡率很高。即使没有呼吸道症状,立即插管和支气管冲洗也能取得最佳治疗效果。对于克服极高气道阻力这一特殊问题,可能需要进行人工通气。皮质类固醇和支气管扩张剂可能会有帮助。