Kappe R, Osterziel K J, Rüchel R, Siehl S
Department of Medicine, University of Heidelberg, Germany.
J Med Vet Mycol. 1993;31(3):259-61. doi: 10.1080/02681219380000311.
We report on four cases of aspergillosis which developed during therapy with fluconazole in patients who were immunosuppressed or granulocytopenic. Fluconazole may obscure the onset of aspergillosis. We feel that it should neither be given prophylactically nor for fever of unknown origin in patients who are at high risk of contracting aspergillosis.
我们报告了4例在接受氟康唑治疗期间发生曲霉病的病例，这些患者均为免疫抑制或粒细胞减少患者。氟康唑可能会掩盖曲霉病的发病。我们认为，对于有感染曲霉病高风险的患者，既不应预防性给予氟康唑，也不应将其用于不明原因发热的患者。
