Ninomiya K, Maruhama Y
1st Department of Internal Medicine, Iwate Medical University, School of Medicine, Morioka.
Rinsho Byori. 1993 Jun;41(6):627-31.
In Japanese, serum cholesterol levels have been increasing. This seems to be due to changes in life style, mainly the increase in dietary fat. Epidemiologic studies in the United States and Europe have shown that patients with hypercholesterolemia have a high risk of ischemic heart disease. Some guidelines for the management of hyperlipidemia have been developed in the United States, Europe, and Japan. The National Cholesterol Education Program (NECP) in the United States divides serum cholesterol level into three grades (desirable: below 200 mg/dl, borderline: between 200 mg/dl and 240 mg/dl, hypercholesterolemia: over 240 mg/dl). Borderline serum cholesterol is also a risk, especially in people complicated by other risk factor(s). As most borderline serum cholesterol seems to be due to polygenic hypercholesterolemia, an attempt to change the diet should be the first recommendation for treatment.
在日本，血清胆固醇水平一直在上升。这似乎是由于生活方式的改变，主要是饮食中脂肪摄入的增加。美国和欧洲的流行病学研究表明，高胆固醇血症患者患缺血性心脏病的风险很高。美国、欧洲和日本已经制定了一些高脂血症管理指南。美国国家胆固醇教育计划（NECP）将血清胆固醇水平分为三个等级（理想水平：低于200mg/dl，临界水平：200mg/dl至240mg/dl之间，高胆固醇血症：超过240mg/dl）。临界血清胆固醇也是一种风险，尤其是在伴有其他危险因素的人群中。由于大多数临界血清胆固醇似乎是由多基因高胆固醇血症引起的，改变饮食的尝试应该是治疗的首要建议。
