p53 protein expression in Reed-Sternberg cells of Hodgkin's disease.
作者信息
Gupta R K, Norton A J, Lister T A, Bodmer J G
机构信息
ICRF Department of Medical Oncology, St. Bartholomew's Hospital, London, England, UK.
出版信息
Leukemia. 1993 Aug;7 Suppl 2:S31-3.
PMID:8361229
Abstract
Hodgkin's disease (HD) is perceived to be a malignant disease of the lymphoid system. One of the main obstacles into the investigation of the cell biology of Hodgkin's disease is the relative paucity of Reed-Sternberg cells (or variants), the presumed neoplastic component of this condition, which often make up less than 1% of the total cell number.
摘要
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