[非选择性β-肾上腺素能阻滞剂对胰岛素诱导低血糖期间血浆胰高血糖素水平的影响]
[Effect of nonselective beta-adrenergic blockade on blood plasma levels of glucagon in plasma during insulin-induced hypoglycemia].
作者信息
Szelechowska M, Kinalska I
机构信息
Kliniki Endokrynologii AM, Białymstoku.
出版信息
Pol Tyg Lek. 1993;48(1-2):27-9.
PMID:8361879
Abstract
An effect of nonselective beta-adrenergic blockade with propranolol on the blood plasma level of glucagon during insulin-induced hypoglycemia was studies in 20 control dogs and 20 alloxan diabetic dogs. Increased sensitivity to exogenous insulin and prolonged hypoglycemia were noted during nonselective beta-adrenergic blockade. However, glucagon response to insulin-induced hypoglycemia following propranolol administration was increased.
摘要
在20只对照犬和20只四氧嘧啶糖尿病犬中研究了普萘洛尔非选择性β-肾上腺素能阻滞对胰岛素诱导低血糖期间血浆胰高血糖素水平的影响。在非选择性β-肾上腺素能阻滞期间，观察到对外源性胰岛素的敏感性增加和低血糖持续时间延长。然而，给予普萘洛尔后，胰高血糖素对胰岛素诱导低血糖的反应增加。
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