Hattner R S
Department of Radiology, University of California, School of Medicine, San Francisco.
Radiol Clin North Am. 1993 Sep;31(5):1029-38.
A nuclear scan maps the distribution of a radiopharmaceutical that is specific for a physiologic property of a targeted tissue. As such, it is not limited by the anatomic changes necessary for CT and MR scans. It is just because of this that maps of specific metabolic precursors of adrenal medullary and cortical hormones offer information crucial to the therapeutic strategy of endocrine hypertension. NP-59 and MIBG scans can specify the nature of abnormalities revealed by anatomic images and because of the ease of surveying the whole body can give transcendent information about lesions remote from the adrenals. In instances when the origin of endocrine hypertension is not forthcoming from CT or MR imaging or when the anatomic and biochemical findings are in conflict, NP-59 or MIBG can almost always provide the answer.
核扫描可绘制出一种放射性药物的分布情况，该药物对目标组织的生理特性具有特异性。因此，它不受CT和磁共振扫描所需的解剖学变化的限制。正因为如此，肾上腺髓质和皮质激素特定代谢前体的图谱为内分泌性高血压的治疗策略提供了至关重要的信息。NP - 59和间碘苄胍（MIBG）扫描可以明确解剖图像所显示异常的性质，并且由于能够轻松对全身进行检查，所以可以提供有关肾上腺以外远处病变的卓越信息。在CT或磁共振成像无法确定内分泌性高血压的病因时，或者解剖学和生化检查结果相互矛盾时，NP - 59或MIBG几乎总能给出答案。
