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Comparative pharmacologic profile of a glycosaminoglycan mixture, Sulodexide, and a chemically modified heparin derivative, Suleparoide.

作者信息

Callas D D, Hoppensteadt D A, Jeske W, Iqbal O, Bacher P, Ahsan A, Fareed J

机构信息

Department of Pharmacology, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois 60153.

出版信息

Semin Thromb Hemost. 1993;19 Suppl 1:49-57.

PMID:8362269
Abstract
摘要

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Sulodexide improves vascular permeability via glycocalyx remodelling in endothelial cells during sepsis.舒洛地特通过改善脓毒症内皮细胞糖萼重塑来改善血管通透性。
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Comparative Anticoagulant and Thrombin Generation Inhibitory Profile of Heparin, Sulodexide and Its Components.肝素、舒洛地特及其成分的抗凝和凝血酶生成抑制特性比较。
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Sulodexide Improves Contraction and Decreases Matrix Metalloproteinase-2 and -9 in Veins Under Prolonged Stretch.
舒洛地特可改善长期牵张状态下静脉的收缩功能并降低基质金属蛋白酶-2 和 -9 的表达。
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