Herder G A
Barneavdelingen, Nordland Sentralsykehus, Bodø.
Tidsskr Nor Laegeforen. 1993 Aug 10;113(18):2247-9.
Few epidemiological studies of infantile autism have been conducted in Norway. A prevalence of four per 10,000 children was found in Nord-Trøndelag. Studies from Sweden, England and Japan show prevalence figures of 2-13 per 10,000. Causal factors of autism are complicated, but many studies in recent years indicate that both genetic and neurological factors are important. The aim of this study was to establish the prevalence of infantile autism in Nordland county and look for causal factors and disabilities among the children. Together with the Autism-Team we found 28 persons, born between 1975 and 1991, who lived in the county in 1992. This gives a prevalence of 5.5 per 10,000. 21 were boys, seven girls, 26 were mentally retarded, 13 had no verbal speech. Nine had epilepsy. 13 children were diagnosed before the age of four. Different diseases and impairments associated with autism were discovered in 19 children. In the case of eight children we found associated disease. When a diagnosis of infantile autism is made, the child should undergo a thorough medical and neurological examination. This should include CT brain scan, EEG, chromosome analysis, and screening for metabolic diseases and intrauterine virus infections. Sometimes examinations of liquor and auditory brain-stem responses are indicated.
挪威针对婴幼儿自闭症开展的流行病学研究较少。在北特伦德拉格郡发现每万名儿童中有4例自闭症患者。瑞典、英国和日本的研究显示自闭症患病率为每万名儿童中有2至13例。自闭症的致病因素很复杂,但近年来许多研究表明,遗传因素和神经因素都很重要。本研究的目的是确定诺尔兰郡婴幼儿自闭症的患病率,并寻找这些儿童的致病因素和残疾情况。我们与自闭症研究团队共同找到了28名于1975年至1991年出生、1992年居住在该郡的人。这得出的患病率为每万名儿童中有5.5例。其中21名是男孩,7名是女孩,26名智力发育迟缓,13名不会说话。9名患有癫痫。13名儿童在4岁之前被确诊。在19名儿童中发现了与自闭症相关的不同疾病和损伤。在8名儿童身上发现了相关疾病。一旦确诊婴幼儿自闭症,儿童应接受全面的医学和神经学检查。这应包括脑部CT扫描、脑电图、染色体分析,以及代谢疾病和宫内病毒感染筛查。有时还需要进行脑脊液检查和听觉脑干反应检查。