Sola Pérez J, Pérez-Guillermo M, Bas Bernal A, Rodriguez Bermejo M
Department of Pathology, Arrixaca University Hospital, Murcia, Spain.
Acta Cytol. 1993 Sep-Oct;37(5):725-8.
We describe the cytopathologic features of two cases of collagenous spherulosis of the breast on fine needle aspiration cytology. The main findings were a moderately rich cellular aspirate, monolayered epithelial clusters with bland nuclei, naked bipolar nuclei and light green (Papanicolaou stain) or pink (Diff-Quik) spherules surrounded by a ring of comma-shaped nuclei resembling myoepithelial cells, located either at the heart of the epithelial clusters or detached from them. We also comment on the differential diagnosis with adenoid cystic carcinoma of the breast, signet-ring carcinoma and myospherulosis.
我们描述了两例乳腺胶原球病在细针穿刺细胞学检查中的细胞病理学特征。主要发现为细胞涂片中等丰富,单层上皮细胞簇,细胞核温和,可见裸核双极核,以及淡绿色(巴氏染色)或粉红色(Diff-Quik染色)的小球体,其周围有一圈类似肌上皮细胞的逗号状细胞核,小球体位于上皮细胞簇中心或与之分离。我们还对乳腺腺样囊性癌、印戒细胞癌和肌球形体病的鉴别诊断进行了讨论。