Bilgrami S, Bartolomeo A, Synnott V, Rickles F R
Division of Hematology-Oncology, University of Connecticut, School of Medicine, Farmington.
Acta Haematol. 1993;89(3):141-3. doi: 10.1159/000204506.
Patients with hemosiderosis who also suffer from coexistent anemia may be unable to tolerate frequent phlebotomies needed for depletion of body iron stores. Chelation therapy, an alternative approach, may be unsuitable for some patients due to allergic reactions, poor response or intolerance of long-duration subcutaneous administration. The use of recombinant human erythropoietin in such patients could increase the hematocrit and improve exercise tolerance allowing for more frequent phlebotomies. We report the successful use of this combined approach in two such patients.
患有血色素沉着症且同时伴有贫血的患者可能无法耐受为耗尽体内铁储备所需的频繁放血治疗。螯合疗法作为一种替代方法，由于过敏反应、反应不佳或对长期皮下给药不耐受，可能不适用于某些患者。在此类患者中使用重组人促红细胞生成素可提高血细胞比容并改善运动耐量，从而允许更频繁地进行放血治疗。我们报告了在两名此类患者中成功使用这种联合方法的情况。
