Hill L M, Guzick D, Peterson C, DiNofrio D, Maloney J, Nedzeksy P
Department of Ultrasound, Magee-Womens Hospital, Pittsburgh, PA 15213.
Am J Obstet Gynecol. 1993 Aug;169(2 Pt 1):347-51. doi: 10.1016/0002-9378(93)90086-x.
The purpose of this study was twofold: (1) to evaluate the relationship between fetal heart circumference and gestational age and (2) to determine the effect, if any, of disturbances in fetal growth on heart circumference.
Heart circumference was measured in 262 women with normal gestations (control group) and in two study groups consisting of 52 large-for-gestational age 32 small-for-gestational age fetuses. Standardized, gestational age-adjusted values in the two study groups were compared with normative data provided by the control group.
There was a close correlation (R2 = 0.94) between heart circumference and gestational age in normally growing fetuses. Disturbances of fetal growth (i.e., macrosomia and growth retardation) were found to have an inconsistent effect on heart circumference.
Heart circumference cannot be used as an independent parameter for gestational age evaluation in fetuses with disturbances of growth.
本研究有两个目的：（1）评估胎儿心脏周长与孕周之间的关系；（2）确定胎儿生长紊乱对心脏周长的影响（若有）。
对262名正常妊娠的女性（对照组）以及由52名大于孕周胎儿和32名小于孕周胎儿组成的两个研究组测量心脏周长。将两个研究组中经孕周调整的标准化值与对照组提供的标准数据进行比较。
正常生长胎儿的心脏周长与孕周之间存在密切相关性（R2 = 0.94）。发现胎儿生长紊乱（即巨大儿和生长迟缓）对心脏周长的影响不一致。
对于生长紊乱的胎儿，心脏周长不能用作评估孕周的独立参数。
