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15-Deoxyspergualin, a novel immunosuppressive drug: studies of the mechanism of action.

作者信息

Tepper M A, Nadler S, Mazzucco C, Singh C, Kelley S L

机构信息

Department of Immunology, Bristol-Myers Squibb Pharmaceutical Research Institute, Wallingford, Connecticut 06492.

出版信息

Ann N Y Acad Sci. 1993 Jun 23;685:136-47. doi: 10.1111/j.1749-6632.1993.tb35860.x.

DOI:10.1111/j.1749-6632.1993.tb35860.x
PMID:8363218
Abstract
摘要

相似文献

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15-Deoxyspergualin, a novel immunosuppressive drug: studies of the mechanism of action.15-去氧精胍菌素，一种新型免疫抑制药物：作用机制研究
Ann N Y Acad Sci. 1993 Jun 23;685:136-47. doi: 10.1111/j.1749-6632.1993.tb35860.x.
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The immunosuppressive agent 15-deoxyspergualin functions by inhibiting cell cycle progression and cytokine production following naive T cell activation.免疫抑制剂15-脱氧精胍菌素通过抑制初始T细胞激活后的细胞周期进程和细胞因子产生发挥作用。
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引用本文的文献

1
Immunosuppressant deoxyspergualin induces apoptotic cell death in dividing cells.免疫抑制剂脱氧精胍菌素可诱导分裂细胞发生凋亡性细胞死亡。
Immunology. 1998 Nov;95(3):370-6. doi: 10.1046/j.1365-2567.1998.00606.x.
2
Deoxyspergualin preferentially inhibits the growth and maturation of anti-CD40-activated surface IgD+ B lymphocytes.去氧精胍菌素优先抑制抗CD40激活的表面IgD+B淋巴细胞的生长和成熟。
Clin Exp Immunol. 1998 Jun;112(3):495-500. doi: 10.1046/j.1365-2249.1998.00602.x.
3
Impact of 15-deoxyspergualin on effector cells in experimental autoimmune diseases of the nervous system in the Lewis rat.
15-脱氧精胍菌素对Lewis大鼠实验性自身免疫性神经系统疾病中效应细胞的影响
Clin Exp Immunol. 1994 Dec;98(3):494-502. doi: 10.1111/j.1365-2249.1994.tb05518.x.