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[具有肿瘤表现的局限性骨化性支气管病,包括阿尔淀粉样变性]

[Localized osteoplastic bronchopathy with tumoral expression, including Al amyloidosis].

作者信息

Costes-Martineau V, Serre I, Roger P, Baldet P, Senac J P, Mary H

机构信息

Service d'Anatomie Pathologie B, Hôpital Lapeyronnie, Montpellier.

出版信息

Ann Pathol. 1993;13(2):111-4.

PMID:8363669
Abstract

We report a case concerning a 65 year old man who suffered from a drug resistant asthma and radiographically visible mass in the right lower lobe of the lung. Pathological studies demonstrated it to be "Bronchopathia Osteoplastica", involving segmental bronchi, with completed hematopoietic metaplasia. This rare dystrophic lesion was associated with localized lambda light chain amyloidosis as was proved by the immunohistochemistry. This association suggests a possible relation between amyloidosis and abnormal osteogenesis.

摘要

我们报告了一例65岁男性患者,该患者患有耐药性哮喘且在右肺下叶有影像学可见的肿块。病理研究表明其为“骨化性支气管病”,累及节段性支气管,伴有完全造血化生。这种罕见的营养不良性病变与局限性λ轻链淀粉样变性有关,免疫组织化学证实了这一点。这种关联提示淀粉样变性与异常骨生成之间可能存在关系。

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