Recombinant expression and partial characterization of the human formyl peptide receptor.
作者信息
Lala A, Sharma A, Sojar H T, Radel S J, Genco R J, De Nardin E
机构信息
Department of Oral Biology, School of Dentistry, State University of New York at Buffalo 14214.
出版信息
Biochim Biophys Acta. 1993 Sep 13;1178(3):302-6. doi: 10.1016/0167-4889(93)90208-7.
PMID:8364044
Abstract
FMLP-receptor DNA was expressed in Escherichia coli. The expressed product could specifically bind FMLP. This is the first-reported expression of a functional FMLP receptor in Escherichia coli. We confirm that receptor glycosylation is not essential for ligand binding. A deletion mutant did not bind FMLP, suggesting that the deleted portion plays a role in ligand binding.
摘要
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