Efremova N V, Topchieva I N
Biokhimiia. 1993 Jul;58(7):1071-6.
The reaction of the complex formation between beta-cyclodextrin and alpha-chymotrypsin conjugates with two-component ethylene oxide copolymers with propylene oxide has been described for the first time. The complex formation has been shown to depend on the mode of distribution of the polymer chains in the conjugate. The complex is a crystalline water-insoluble compound; its stoichiometric composition has been determined. The alpha-chymotrypsin conjugate with polyethylene glycol forms a water-soluble complex with beta-cyclodextrin.
