7-氯-3-(4-甲基-1-哌嗪基)-4H-1,2,4-苯并噻二嗪-1,1-二氧化物，一种新型抗高血压药物。 - Suppr | 超能文献

7-chloro-3-(4-methyl-1-piperazinyl)-4H-1,2,4-benzothiadiazine-1,1-dioxide, a new antihypertensive agent.

作者信息

Shimizu M, Yoshida K, Kadokawa T, Hatano N, Kuwashima J

出版信息

Experientia. 1977 Jan 15;33(1):55-7. doi: 10.1007/BF01936752.

DOI:10.1007/BF01936752

Abstract

摘要

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7-chloro-3-(4-methyl-1-piperazinyl)-4H-1,2,4-benzothiadiazine-1,1-dioxide, a new antihypertensive agent.7-氯-3-(4-甲基-1-哌嗪基)-4H-1,2,4-苯并噻二嗪-1,1-二氧化物，一种新型抗高血压药物。

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[3-(Alpha-methylbenzyl)-6-chlor-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, a new saluretic. 2].

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Chloro-substituted 3-alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides as ATP-sensitive potassium channel activators: impact of the position of the chlorine atom on the aromatic ring on activity and tissue selectivity.氯取代的 3-烷基氨基-4H-1,2,4-苯并噻二嗪 1,1-二氧化物作为 ATP 敏感性钾通道激活剂：氯原子在芳环上位置对活性和组织选择性的影响。

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Impact of the nature of the substituent at the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides on their opening activity toward ATP-sensitive potassium channels.3-位取代基的性质对 4H-1,2,4-苯并噻二嗪 1,1-二氧化物打开 ATP 敏感性钾通道活性的影响。

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[3-Amino-2H-1,2,4-benzothiadiazine-1,1-dioxides with antihypertensive and possibly diabetogenic activity (author's transl)].具有抗高血压及可能致糖尿病活性的 3 - 氨基 - 2H - 1,2,4 - 苯并噻二嗪 - 1,1 - 二氧化物（作者译）

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本文引用的文献

1

EFFECT OF ISCHEMIA ON KNOWN SUBSTRATES AND COFACTORS OF THE GLYCOLYTIC PATHWAY IN BRAIN.缺血对脑糖酵解途径已知底物和辅助因子的影响。

J Biol Chem. 1964 Jan;239:18-30.

2

Development of a strain of spontaneously hypertensive rats.一种自发性高血压大鼠品系的培育

Jpn Circ J. 1963 Mar;27:282-93. doi: 10.1253/jcj.27.282.