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Comparative studies of intracellular activity, secretion and multiple forms spectra of human skin fibroblast alpha-L-fucosidase in the normaland after sucrose load.

作者信息

Beyer E M, Ivleva T S, Artykova G T

机构信息

Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow.

出版信息

Biochem Mol Biol Int. 1993 Jun;30(2):367-75.

PMID:8364414
Abstract

Activity and multiple forms of intracellular and secreted alpha-L-fucosidases from human skin fibroblasts were studied in normal and sucrose-loaded cells--modelling intralysosomal nonhydrolyzable products' accumulation in vitro. Certain differences in secretion levels were found after sucrose load for alpha-L-fucosidases from embryonal and postnatal cell lines. Different effects of sucrose load on multiple forms' spectra of the intracellular and secreted alpha-L-fucosidases from embryonal and postnatal fibroblasts were revealed.

摘要

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