Kalra G S, Arora R, Koshy G, Khanna R, Khalilullah M
Department of Cardiology, G.B. Pant Hospital, New Delhi.
Indian Heart J. 1993 Mar-Apr;45(2):109-11.
We attempted balloon dilatation of native coarctation of aorta in 11 consecutive neonates and infants (age range 28 days-12 months, mean 4.6 +/- 4 months, all males) presenting with congestive heart failure. The peak to peak aorto-aortic systolic pressure gradient fell from 60 +/- 21 mmHg to 13 +/- 7 mmHg (range 0-30 mmHg) (p < 0.001). The diameter of coarcted segment increased from 2.5 +/- 0.65 mm (range 2-3.4 mm) to 5.4 +/- 0.9 mm (range 4-6.4 mm) (p < 0.001). No patient required surgical intervention. The peak instantaneous aorto-aortic systolic Doppler pressure gradient at 17.5 +/- 8.8 months (range 2-21 months) did not show any significant change (mean 17.5 +/- 8.89 mmHg range 0-30 mmHg). All patients except one showed improvement in congestive heart failure. None developed restenosis. On the basis of this experience we recommend that balloon dilatation of native coarctation of aorta in infants in congestive heart failure is a safe and effective procedure.
我们对11例连续的患有充血性心力衰竭的新生儿和婴儿（年龄范围28天至12个月，平均4.6±4个月，均为男性）尝试进行主动脉缩窄的球囊扩张术。主动脉-主动脉收缩压峰峰值梯度从60±21 mmHg降至13±7 mmHg（范围0至30 mmHg）（p<0.001）。缩窄段直径从2.5±0.65 mm（范围2至3.4 mm）增加至5.4±0.9 mm（范围4至6.4 mm）（p<0.001）。无患者需要手术干预。在17.5±8.8个月（范围2至21个月）时的主动脉-主动脉收缩期瞬时多普勒压力峰峰值梯度未显示任何显著变化（平均17.5±8.89 mmHg，范围0至30 mmHg）。除1例患者外，所有患者的充血性心力衰竭均有改善。无一例发生再狭窄。基于这一经验，我们建议对患有充血性心力衰竭的婴儿进行主动脉缩窄的球囊扩张术是一种安全有效的方法。
