Robinson F C, Satterwhite K, Potter C, Craddock K, Beyoglu S A
Department of Medicine, Howard University Hospital, Washington, DC 20060.
J Natl Med Assoc. 1993 Jun;85(6):452-6.
Thallium-201 stress scintigraphy (TSS) and echocardiography were performed on 60 consecutive black male hypertensives and compared to 60 sex-, race-, and age-matched controls. We found a higher prevalence of left ventricular hypertrophy with repolarization abnormality in the hypertensive group; 32 of 60 (53%), compared to 10 of 60 (17%) of the controls, P < .05. Echocardiographically determined left ventricular mass index revealed a significantly higher mean value in the hypertensive group of 147 +/- 57 compared to 124 +/- 34 in the control group, P < .001. Thirty-one of 60 (52%) of the hypertensive group had a normal TSS compared to 22 of 60 (37%) of the controls. A total of 68 (38 fixed and 30 reversible) perfusion defects were noted in the hypertensive group compared to 74 (55 fixed and 19 reversible) in the controls. The severity of clinical syndromes associated with myocardial ischemia were noted in increased incidence in the presence of left ventricular hypertrophy and left ventricular mass index was noted to be predictive of severity of coronary disease independent of the standard risk factors.
对60例连续的黑人男性高血压患者进行了铊-201负荷闪烁扫描（TSS）和超声心动图检查，并与60例性别、种族和年龄匹配的对照者进行比较。我们发现高血压组左心室肥厚伴复极异常的患病率更高；60例中有32例（53%），而对照组60例中有10例（17%），P<0.05。超声心动图测定的左心室质量指数显示，高血压组的平均值显著高于对照组，分别为147±57和124±34，P<0.001。高血压组60例中有31例（52%）TSS正常，而对照组60例中有22例（37%）正常。高血压组共发现68处灌注缺损（38处固定性和30处可逆性），而对照组为74处（55处固定性和19处可逆性）。在存在左心室肥厚的情况下，与心肌缺血相关的临床综合征的严重程度发生率增加，并且左心室质量指数被认为可独立于标准危险因素预测冠心病的严重程度。
