Yoshitake S, Matsumoto K, Miyagawa A, Mori M, Kitano T, Oda S, Taniguchi K, Honda N
Department of Anesthesiology, Oita Medical University.
Masui. 1993 Aug;42(8):1233-6.
Congenital insensitivity to pain with anhidrosis is a rare disorder but several clinical anesthetic experiences have been reported in Japan. We anesthetized a patient with this disorder for orthopedic operation with a low concentration of sevoflurane under monitoring of body temperature and we measured the concentrations of plasma ADH, cortisol and catecholamines levels before, during and after the operation. There were no problems during anesthesia and the patient awoke rapidly. ADH, cortisol and epinephrine concentrations showed slight elevations during and after the operation. The management of intraoperative body temperature and the necessary level of anesthesia were also discussed.
