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肺炎链球菌分离株的血清型分布、抗菌药物敏感性及临床特征

Serotype distribution, antimicrobial susceptibility, and clinical character of Streptococcus pneumoniae isolates.

作者信息

Ismaeel N A

机构信息

Department of Microbiology, College of Medicine and Allied Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.

出版信息

Microbios. 1993;74(301):233-40.

PMID:8366829
Abstract

Strains of Streptococcus pneumoniae (268 in toto) isolated from different infected sites in patients were serotyped, their susceptibilities to antimicrobial agents were determined, and the laboratory data were correlated with clinical information. The distribution pattern of serogroups and serotypes was different in paediatric patients (< 18 years old) when compared with that of adults. Overall, 91% of the strains were represented in a 23-valent vaccine. Only eight patients received pneumococcal vaccine before infection, and only 18 strains (6.7%) were moderately susceptible or resistant to one or more of the antimicrobial agents tested. Five strains were moderately susceptible to penicillin G, and not one was fully resistant.

摘要

对从患者不同感染部位分离出的肺炎链球菌菌株(共268株)进行血清分型,测定其对抗菌药物的敏感性,并将实验室数据与临床信息进行关联。与成人相比,儿科患者(<18岁)的血清群和血清型分布模式有所不同。总体而言,91%的菌株包含在23价疫苗中。只有8名患者在感染前接种了肺炎球菌疫苗,只有18株菌株(6.7%)对一种或多种测试抗菌药物中度敏感或耐药。5株菌株对青霉素G中度敏感,无一株完全耐药。

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