Wise K A, Speed B R, Ellis D H, Andrew J H
Microbiology Department, Wollongong Hospital, NSW, Australia.
Pathology. 1993 Apr;25(2):187-9. doi: 10.3109/00313029309084797.
Two fatal infections caused by Scedosporium inflatum in immunocompromised patients are described. One patient developed peritonitis with this fungus 3 mths post renal transplantation. After a stormy course in the intensive care unit he eventually died. The other patient was suffering from non-Hodgkin's lymphoma and showed persistent neutropenia. Progressive deterioration occurred, and disseminated fungal infection was found at post mortem. Both isolates were resistant to all commonly available antifungal agents.
本文描述了两例由膨胀瓶霉引起的免疫功能低下患者的致命感染。一名患者在肾移植后3个月发生了由这种真菌引起的腹膜炎。在重症监护病房经历了一段波折的病程后，他最终死亡。另一名患者患有非霍奇金淋巴瘤，表现为持续性中性粒细胞减少。病情逐渐恶化，尸检时发现有播散性真菌感染。两株分离株对所有常用抗真菌药物均耐药。
