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[牙源性囊肿——组织发生、组织学、可能发生肿瘤转化的潜能]

[Odontogenic cysts--histogenesis, histology, potential for possible neoplastic transformation].

作者信息

Dubiel-Bigaj M

机构信息

Zak+ad Patomorfologii Klinicznej i Doświadczalnej AM, Kraków.

出版信息

Patol Pol. 1993;44(2):45-54.

PMID:8367208
Abstract

Epithelial odontogenic cyst develop either in result od peridental inflammation-radicular cyst, or in result of developmental disturbances in the course of the odontogenesis. The latter are divided into primordial and dentigerous cysts. Some odontogenic cysts are lined with squamous keratotic epithelium -ortho- or parakeratotic type. The latter is characterized by higher recurrence rate and malignant potential. Primary intraosseous carcinoma (PIOC) both keratizing and nonkeratizing might originate in keratocyst. Mucoepidermoid carcinoma and occasionally other benign and malignant sialogenic tumors might originate in keratocyst either. In addition in the jaw-bones with the odontogenic cyst or even without the cyst, squamous odontogenic tumor (SOT) can develop or so-called squamous odontogenic tumor-like proliferation in odontogenic cyst (SOT-LPOC). PIOC is a cancer of low grade malignant potential. Biology of SOT and SOT-LPOC in not elucidated yet as these are not frequently occurred lesion.

摘要

上皮性牙源性囊肿可因牙周炎症(根端囊肿)而发生,也可因牙发生过程中的发育障碍而形成。后者又分为始基囊肿和含牙囊肿。一些牙源性囊肿内衬鳞状角化上皮——正角化或副角化型。后者的特点是复发率较高且有恶变潜能。原发性骨内癌(PIOC),无论是角化型还是非角化型,都可能起源于角化囊肿。黏液表皮样癌以及偶尔其他良性和恶性涎腺肿瘤也可能起源于角化囊肿。此外,在有牙源性囊肿甚至无囊肿的颌骨中,可发生鳞状牙源性肿瘤(SOT),或在牙源性囊肿中出现所谓的鳞状牙源性肿瘤样增生(SOT-LPOC)。PIOC是一种具有低度恶性潜能的癌症。由于SOT和SOT-LPOC并不常见,其生物学特性尚未阐明。

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