Burleson M L, Milsom W K
Department of Zoology, University of British Columbia, Vancouver, Canada.
Respir Physiol. 1993 Jul;93(1):97-110. doi: 10.1016/0034-5687(93)90071-h.
Afferent neural activity was recorded from sensory receptors innervated by the glossopharyngeal nerve (cranial nerve IX) in isolated, perfused first gill arch preparations from rainbow trout. The present study demonstrates the presence of every major type of peripheral cardio-respiratory receptor described in fish in this preparation. Oxygen-sensitive chemoreceptors responsive to internal and/or external hypoxia and cyanide were present. Qualitatively these receptors behaved in an identical fashion which was also similar to that described for mammalian carotid body chemoreceptors. About 5% of the sensory receptors examined were O2-sensitive. proprioceptors were the most numerous receptor type identified and were sensitive to mechanical stimulation of the arch, rakers or filaments. Finally, baroreceptors, the least numerous class of receptor identified, were also present with activity that was altered in response to changes in perfusion pressure. While the reflex responses elicited by the stimulation of these receptors were not addressed in this study, it is likely that these receptors contribute to the reflex cardio-respiratory responses to changes in gill perfusion, gill deflection and hypoxia (environmental or internal) described in fishes. These data thus support suggestions concerning homologies between the first gill arch of teleosts and the carotid bodies of mammals and the importance of the first gill arch in trout in cardio-respiratory control.
在虹鳟鱼离体灌注的第一鳃弓标本中，记录了由舌咽神经（第九对脑神经）支配的感觉感受器的传入神经活动。本研究证明了在此标本中存在鱼类中描述的每种主要类型的外周心肺感受器。存在对内部和/或外部缺氧及氰化物有反应的氧敏感化学感受器。从定性角度来看，这些感受器的行为方式相同，这也与哺乳动物颈动脉体化学感受器的情况相似。所检测的感觉感受器中约5%对氧气敏感。本体感受器是鉴定出的数量最多的感受器类型，对鳃弓、鳃耙或鳃丝的机械刺激敏感。最后，压力感受器是鉴定出的数量最少的感受器类型，也存在，其活动会因灌注压力的变化而改变。虽然本研究未探讨这些感受器受刺激引发的反射反应，但这些感受器很可能参与了鱼类中描述的对鳃灌注、鳃偏转和缺氧（环境或内部）变化的心肺反射反应。因此，这些数据支持了有关硬骨鱼第一鳃弓与哺乳动物颈动脉体之间同源性以及第一鳃弓在虹鳟鱼心肺控制中重要性的观点。
