DeVore P A
Department of Community and Family Medicine, Georgetown University School of Medicine, Washington, DC.
South Med J. 1993 Sep;86(9):1008-10. doi: 10.1097/00007611-199309000-00007.
Overweight and obesity are generally considered to have a negative impact on longevity because of their association with many diseases, including hypertension, diabetes, coronary artery disease, osteoarthritis, and certain types of cancer. Nevertheless, some authors, notably Ancel Keys, have concluded that being overweight improves one's chances for longevity. I studied 122 consecutive patients who had comprehensive geriatric assessment with regard to their body mass index, responses to Wolinsky's Nutritional Risk Index, and serum albumin levels. There was a high prevalence of overweight (60% of men and 45.6% of women). This fact, coupled with the observed low prevalence of underweight subjects, tends to support Keys' statement concerning the benefit of being overweight. However, the relative absence of significant obesity supports the impression that significantly obesity reduces prospects for longevity. Although serum albumin measurements were obtained for only 38 subjects, the fact that the value was low in only one instance--in the case of a person who was seriously ill--suggests that obtaining routine serum albumin measurements in ambulatory, community-dwelling elderly people is not cost-effective.
超重和肥胖通常被认为会对寿命产生负面影响，因为它们与许多疾病相关，包括高血压、糖尿病、冠状动脉疾病、骨关节炎和某些类型的癌症。然而，一些作者，尤其是安塞尔·基斯，得出结论认为超重会提高人的长寿几率。我研究了122名连续接受全面老年评估的患者，评估内容包括他们的体重指数、对沃林斯基营养风险指数的反应以及血清白蛋白水平。超重的患病率很高（男性为60%，女性为45.6%）。这一事实，再加上观察到的体重过轻受试者的低患病率，倾向于支持基斯关于超重有益的说法。然而，严重肥胖相对较少这一情况支持了这样一种观点，即严重肥胖会降低长寿的几率。虽然仅对38名受试者进行了血清白蛋白测量，但在仅一例中（一名重病患者）该值较低这一事实表明，在非卧床、居住在社区的老年人中进行常规血清白蛋白测量并不具有成本效益。
