Hamel P, Doray B, Teasdale F, Bard H
Hôpital Sainte-Justine, département de pédiatrie, Université de Montréal, Québec, Canada.
Union Med Can. 1993 Jul-Aug;122(4):271-3.
In order to evaluate our hospital center needs for extracorporeal membrane oxygenation (ECMO), a retrospective study was carried out over a two-year-period to determine the mortality rates of infants < or = 35 weeks of gestation and > or = 2000 grams with severe respiratory failure. The data was obtained from a perinatal center that serves a population that has 50,000 newborn deliveries per year. During the period of the study there were 75 infants meeting the above criteria admitted to the NICU with severe respiratory failure (defined as need for mechanical ventilation and 100% O2). Forty-four patients were excluded because of improvement of their respiratory status on conventional therapy, and 16 were ineligible for ECMO because of their primary diagnosis. Of the 15 infants considered ECMO candidates, there were 2 deaths as a result of streptococcal beta hemolytic septicemia. The result of this study showed that few infants in the population served by this perinatal center would have benefited from ECMO.
为评估我院中心对体外膜肺氧合(ECMO)的需求,我们进行了一项为期两年的回顾性研究,以确定孕周≤35周且体重≥2000克的重症呼吸衰竭婴儿的死亡率。数据来自一个每年有50000例新生儿分娩的围产期中心。在研究期间,有75例符合上述标准的婴儿因重症呼吸衰竭(定义为需要机械通气和100%氧气)入住新生儿重症监护病房(NICU)。44例患者因常规治疗后呼吸状况改善而被排除,16例因初步诊断不符合ECMO治疗条件。在15例被认为适合ECMO治疗的婴儿中,有2例因β溶血性链球菌败血症死亡。本研究结果表明,在这个围产期中心服务的人群中,很少有婴儿能从ECMO治疗中获益。