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[体外膜肺氧合(ECMO)。一、西班牙真的需要它吗?]

[Extracorporeal membrane oxygenation (ECMO). I. Is it really needed in Spain?].

作者信息

Valls i Soler A, López Herrera M C, López de Heredia y Goya J, Román Echevarría L, Fernández-Ruanova B

机构信息

Departamento de Pediatría, Hospital de Cruces, Facultad de Medicina, Universidad del País Vasco, Barakaldo, Bizkaia.

出版信息

An Esp Pediatr. 1997 Mar;46(3):261-5.

PMID:9173846
Abstract

OBJECTIVE

Extracorporeal membrane oxygenation (ECMO) is a cardiorespiratory support technique used to treat newborns with severe respiratory insufficiency. ECMO has not been used yet in newborns in Spain, with its necessity being question. The aim of this study was to evaluate the need for ECMO for respiratory or cardiac cases in our neonatal population, as well as to study the predictive capacity of several respiratory indices.

PATIENTS AND METHODS

A retrospective observational study was carried out. Data from 2,133 newborns admitted during a 48 month period was reviewed. Babies were considered ECMO candidates if they died of respiratory failure or after surgery for a cardiac defect and if they had no ECMO exclusion criteria. The capacity of several respiratory indices to predict mortality was analyzed.

RESULTS

We considered 16 babies who died to be ECMO candidates, 6 with respiratory failure (1/3,028 live births) and 10 with cardiac defects 3 of them inborn (1/6,057). The total ECMO need was 1/2019 live births. None of the oxygenation indices studied accurately predicted the 80% mortality rate.

CONCLUSIONS

In Spain, it is necessary to start several neonatal ECMO programs since some 200 newborn infants with severe respiratory failure or cardiac defects could benefit from such a program annually.

摘要

目的

体外膜肺氧合(ECMO)是一种用于治疗严重呼吸功能不全新生儿的心肺支持技术。西班牙尚未在新生儿中使用ECMO,其必要性受到质疑。本研究的目的是评估我们新生儿群体中呼吸或心脏病例对ECMO的需求,以及研究几种呼吸指标的预测能力。

患者与方法

进行了一项回顾性观察研究。回顾了48个月期间收治的2133例新生儿的数据。如果婴儿死于呼吸衰竭或因心脏缺陷手术后死亡,且没有ECMO排除标准,则被视为ECMO候选者。分析了几种呼吸指标预测死亡率的能力。

结果

我们认为16例死亡婴儿为ECMO候选者,6例呼吸衰竭(每3028例活产中有1例),10例心脏缺陷,其中3例为先天性(每6057例活产中有1例)。ECMO的总需求为每2019例活产中有1例。所研究的氧合指标均未准确预测80%的死亡率。

结论

在西班牙,有必要启动多个新生儿ECMO项目,因为每年约有200例患有严重呼吸衰竭或心脏缺陷的新生儿可能从此类项目中受益。

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