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[原发性非梗阻性巨输尿管的临床病程:我们系列病例分析]

[Clinical course of primary non-obstructive megaureter: analysis of our series].

作者信息

Gómez Fraile A, Antón-Pacheco J, Aransay Bramtot A, López Vázquez F, Serrano C, Manrique A

机构信息

Sección de Urología Pediátrica, Hospital 12 de Octubre.

出版信息

Actas Urol Esp. 1993 Jun;17(6):351-6.

PMID:8368100
Abstract

Due to the widespread use of obstetrical ultrasonography with concomitant fetal screening, congenital uropathies are usually diagnosed in asymptomatic neonates. The main issue is to distinguish those cases of dilatation which are clearly obstructive and need surgical treatment from those which are within the normal anatomical range. Out of 47 patients with primary megaureter, 23 were nonobstructive, these are the aim of our study. There were 16 males and 7 females; 13 were located on the left side, 7 on the right side and 3 were bilateral, adding up to 26 reno-ureteral units. Prenatal diagnosis was performed in 16 cases, the eldest patient diagnosed was nine. All infants were evaluated with ultrasonography, voiding cystourethrography, excretory urography and diuresis renography. The latter has been the most important test inducing us to adopt a conservative attitude. Differential renal function was more than 40% in 24 units and in 2 was more than 35%. Diuretic renograms were type IIIa (Dilated non obstructed) in 19 cases and IIIb (Dilated partially obstructed) in 7. There were 2 cases with vesicoureteral reflux in the contralateral system. We have performed ultrasonography and diuresis renography during the follow-up. There were 8 cases with type I (Normal) renograms and 17 cases with type IIIa. Only one patient developed an obstruction and was operated on. In every case differential renal function did not deteriorate. In 9 cases urography was performed in order to see the anatomical changes. They have remained asymptomatic during the follow-up except for two cases which presented urinary tract infection. BUN, creatinine and other biochemical figures remained within normal ranges.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

由于产科超声检查及随之而来的胎儿筛查广泛应用,先天性尿路疾病通常在无症状新生儿中被诊断出来。主要问题是将那些明显梗阻性扩张且需要手术治疗的病例与处于正常解剖范围内的病例区分开来。在47例原发性巨输尿管患者中,23例为非梗阻性,这些是我们研究的对象。其中男性16例,女性7例;左侧13例,右侧7例,双侧3例,共计26个肾输尿管单位。16例进行了产前诊断,诊断时年龄最大的患者为9岁。所有婴儿均接受了超声检查、排尿性膀胱尿道造影、排泄性尿路造影和利尿肾图检查。后者是促使我们采取保守态度的最重要检查。24个单位的分肾功能超过40%,2个单位超过35%。利尿肾图19例为IIIa型(扩张但无梗阻),7例为IIIb型(扩张且部分梗阻)。对侧系统中有2例存在膀胱输尿管反流。随访期间我们进行了超声检查和利尿肾图检查。肾图为I型(正常)的有8例,IIIa型的有17例。只有1例患者出现梗阻并接受了手术。在每例中,分肾功能均未恶化。9例进行了尿路造影以观察解剖结构变化。除2例出现尿路感染外,他们在随访期间一直无症状。血尿素氮、肌酐及其他生化指标均保持在正常范围内。(摘要截取自250字)

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