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Comparison of the binding parameters to melanoma cells of antihuman high molecular weight-melanoma associated antigen (HMW-MAA) monoclonal antibodies (mAb) and syngeneic anti-anti-idiotypic (anti-anti-id) mAb.

作者信息

Chen Z J, Ferrone S

机构信息

Department of Microbiology and Immunology, New York Medical College, Valhalla 10595.

出版信息

Ann N Y Acad Sci. 1993 Aug 12;690:398-401. doi: 10.1111/j.1749-6632.1993.tb44043.x.

DOI:10.1111/j.1749-6632.1993.tb44043.x
PMID:8368768
Abstract
摘要

相似文献

1
Comparison of the binding parameters to melanoma cells of antihuman high molecular weight-melanoma associated antigen (HMW-MAA) monoclonal antibodies (mAb) and syngeneic anti-anti-idiotypic (anti-anti-id) mAb.抗人高分子量黑素瘤相关抗原（HMW-MAA）单克隆抗体（mAb）与同源抗抗独特型（抗抗Id）mAb对黑素瘤细胞结合参数的比较。
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Idiotypic cascade in the human high molecular weight melanoma-associated antigen system: fine specificity and idiotypic profile of anti-anti-idiotypic monoclonal antibodies.人类高分子量黑色素瘤相关抗原系统中的独特型级联：抗抗独特型单克隆抗体的精细特异性和独特型谱
Eur J Immunol. 1993 Jul;23(7):1671-7. doi: 10.1002/eji.1830230741.
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Modulation by adjuvants and carriers of the immunogenicity in xenogeneic hosts of mouse anti-idiotypic monoclonal antibody MK2-23, an internal image of human high molecular weight-melanoma associated antigen.佐剂和载体对小鼠抗独特型单克隆抗体MK2-23（人高分子量黑色素瘤相关抗原的内影像）在异种宿主中的免疫原性的调节作用
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Human high molecular weight-melanoma associated antigen mimicry by an anti-idiotypic antibody: characterization of the immunogenicity and the immune response to the mouse monoclonal antibody IMel-1.一种抗独特型抗体对人高分子量黑色素瘤相关抗原的模拟：小鼠单克隆抗体IMel-1的免疫原性及免疫反应特性
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Human high molecular weight melanoma-associated antigen (HMW-MAA) mimicry by mouse anti-idiotypic monoclonal antibody MK2-23: induction of humoral anti-HMW-MAA immunity and prolongation of survival in patients with stage IV melanoma.小鼠抗独特型单克隆抗体MK2-23对人高分子量黑色素瘤相关抗原（HMW-MAA）的模拟：诱导体液抗HMW-MAA免疫及延长IV期黑色素瘤患者生存期
Proc Natl Acad Sci U S A. 1992 Jan 15;89(2):466-70. doi: 10.1073/pnas.89.2.466.
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Human high molecular weight melanoma-associated antigen mimicry by mouse antiidiotypic monoclonal antibody MK2-23. Characterization of the immunogenicity in syngeneic hosts.小鼠抗独特型单克隆抗体MK2-23模拟人高分子量黑色素瘤相关抗原。同基因宿主中免疫原性的特征。
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Human high molecular weight-melanoma associated antigen mimicry by mouse anti-idiotypic MAb MK2-23. Immunohistochemical analysis of the reactivity of anti-anti-idiotypic MAb with surgically removed melanoma lesions.小鼠抗独特型单克隆抗体MK2-23模拟人高分子量黑色素瘤相关抗原。抗抗独特型单克隆抗体与手术切除的黑色素瘤病灶反应性的免疫组织化学分析。
Int J Cancer. 1995 Jan 27;60(3):334-40. doi: 10.1002/ijc.2910600310.
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Human high-molecular-weight melanoma-associated antigen mimicry by mouse antiidiotypic monoclonal antibody TK7-371.小鼠抗独特型单克隆抗体TK7-371模拟人高分子量黑色素瘤相关抗原
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Human high molecular weight-melanoma associated antigen mimicry by mouse anti-idiotypic monoclonal antibody MK2-23: modulation of the immunogenicity in patients with malignant melanoma.小鼠抗独特型单克隆抗体MK2-23模拟人高分子量黑色素瘤相关抗原：对恶性黑色素瘤患者免疫原性的调节
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Kinetics of the immune response and regression of metastatic lesions following development of humoral anti-high molecular weight-melanoma associated antigen immunity in three patients with advanced malignant melanoma immunized with mouse antiidiotypic monoclonal antibody MK2-23.三名晚期恶性黑色素瘤患者用小鼠抗独特型单克隆抗体MK2-23免疫后，体液抗高分子量黑色素瘤相关抗原免疫反应的动力学及转移病灶的消退情况。
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1
Cancer immunotherapy targeting the high molecular weight melanoma-associated antigen protein results in a broad antitumor response and reduction of pericytes in the tumor vasculature.针对高分子量黑色素瘤相关抗原蛋白的癌症免疫疗法可产生广泛的抗肿瘤反应，并减少肿瘤脉管系统中的周细胞。
Cancer Res. 2008 Oct 1;68(19):8066-75. doi: 10.1158/0008-5472.CAN-08-0287.