Elvin A, Wilander E, Oberg K, Eriksson B, Lindgren P G
Department of Diagnostic Radiology, Akademiska Sjukhuset, Uppsala, Sweden.
Acta Radiol. 1993 Sep;34(5):474-7.
Twenty-five patients with known neuroendocrine tumour disease were biopsied with 1.2 mm and 0.9 mm biopsy-gun needles to evaluate the respective diagnostic accuracy of the 2 needle sizes. The influence of treatment-related fibrosis on the histopathological diagnosis was also evaluated. The overall diagnostic accuracy with the 0.9 mm needle was 69% as compared to 92% with the 1.2 mm needle. This difference, however, seems more related to needle guiding difficulties with the 0.9 mm needle than to insufficient tissue yield. When the tumour was hit with both the 0.9 and the 1.2 mm needle the tissue yield was inferior with the 0.9 mm needle in only one of 16 cases. The increased amount of fibrous tissue due to interferon treatment did not seem to negatively influence the diagnostic accuracy.
对25例已知患有神经内分泌肿瘤疾病的患者,分别使用1.2毫米和0.9毫米的活检枪针进行活检,以评估这两种针径各自的诊断准确性。同时还评估了治疗相关纤维化对组织病理学诊断的影响。0.9毫米针的总体诊断准确率为69%,而1.2毫米针为92%。然而,这种差异似乎更多与0.9毫米针的穿刺引导困难有关,而非组织获取不足。当0.9毫米针和1.2毫米针均穿刺到肿瘤时,在16例中的仅1例中,0.9毫米针获取的组织量较少。干扰素治疗导致的纤维组织量增加似乎并未对诊断准确性产生负面影响。