Akai M, Shirasaki Y, Tateishi T
Department of Orthopaedics, Ichihara Hospital, Teikyo University School of Medicine, Chiba, Japan.
Biomed Mater Eng. 1993 Summer;3(2):67-73.
The purpose of this study was to analyze the joint stiffness after immobilization in a rat's lower extremity model. Rat knee joints were surgically immobilized in a full flexed position for periods of up to 7 weeks with or without intra-articular intervention. The biomechanical analysis was assessed by measuring the bone-joint-bone sample as a cantilever. Measurement was performed with (a) knee flexion angle with gravity, (b) fast Fourier transform analysis of time-dependent mechanical noise with random frequencies, and (c) dynamic stiffness and loss tangent with sinusoidal vibration at a certain frequency. The results showed that the conventional static mechanical test could not detect the intraarticular changes of the whole knee joint. The measurement of the viscoelastic properties covering wide frequencies revealed that an accurate change occurred.
本研究的目的是在大鼠下肢模型中分析固定后关节僵硬情况。通过手术将大鼠膝关节固定于完全屈曲位长达7周，有无关节内干预。通过将骨-关节-骨样本作为悬臂梁进行测量来评估生物力学分析。测量内容包括：(a) 重力作用下的膝关节屈曲角度；(b) 对具有随机频率的随时间变化的机械噪声进行快速傅里叶变换分析；(c) 在特定频率下通过正弦振动测量动态刚度和损耗角正切。结果表明，传统的静态力学测试无法检测到整个膝关节的关节内变化。对涵盖较宽频率范围的粘弹性特性进行测量后发现发生了精确的变化。
