在印度南部韦洛尔分离出的大肠杆菌粪便菌株中，TEM-1β-内酰胺酶基因向不同质粒的传播。

Dissemination of the TEM-I beta-lactamase gene into disparate plasmids in faecal strains of Escherichia coli isolated in Vellore, south India.

作者信息

Thomson C J, Tait S, Jesudason M V, Amyes S G

机构信息

Department of Medical Microbiology, Medical School, University of Edinburgh, Scotland.

出版信息

J Infect. 1993 Jul;27(1):47-50. doi: 10.1016/0163-4453(93)93698-4.

DOI:10.1016/0163-4453(93)93698-4

PMID:8370945

Abstract

The genetic basis for ampicillin resistance in commensal strains of Escherichia coli isolated in Vellore, south India has been examined. Of the 58 strains tested, 41% could transfer ampicillin resistance to a standard E. coli host strain. With the exception of one isolate, transferable ampicillin resistance was shown to result from the presence of the TEM-I beta-lactamase which was found on a wide variety of plasmid types.

摘要

对印度南部韦洛尔分离出的大肠杆菌共生菌株中氨苄青霉素耐药性的遗传基础进行了研究。在测试的58株菌株中，41%能够将氨苄青霉素耐药性转移至标准大肠杆菌宿主菌株。除了一个分离株外，可转移的氨苄青霉素耐药性被证明是由TEM-1β-内酰胺酶的存在导致的，该酶存在于多种质粒类型上。