Jones D M, Mallard R H
Public Health Laboratory Service, Withington Hospital, Manchester, U.K.
J Infect. 1993 Jul;27(1):83-8. doi: 10.1016/0163-4453(93)93978-d.
The age incidence of meningococcal infections occurring between 1984 and 1991 in England and Wales was determined from data submitted with isolates to the Meningococcal Reference Laboratory for England and Wales. The incidence was maximum at 6 months of age and thereafter declined sharply to the age of 4 years. It was followed by a small secondary peak at 17-18 years. There was a relative excess of group B infections in the early months of life and, although group B and group C infections both peaked at 6 months of age, the latter did not decline until after the age of 9 months. Certain strains of meningococci were more likely to be associated with disease in older children and young adults.
根据提交给英格兰和威尔士脑膜炎球菌参考实验室的分离菌株数据,确定了1984年至1991年期间英格兰和威尔士脑膜炎球菌感染的年龄发病率。发病率在6个月大时最高,此后急剧下降至4岁。随后在17 - 18岁出现一个小的次高峰。在生命的最初几个月,B群感染相对较多,尽管B群和C群感染都在6个月大时达到高峰,但C群感染直到9个月大后才下降。某些脑膜炎球菌菌株更有可能与大龄儿童和年轻人的疾病相关。