Hedden R J, Husseinzadeh N, Bracken R B
Department of Surgery, University of Cincinnati Medical Center, Ohio.
J Urol. 1993 Oct;150(4):1135-7. doi: 10.1016/s0022-5347(17)35707-5.
Cystectomy remains one of the standard treatments for women with locally advanced (stage C) urethral cancer, or stage A or B lesions that have failed radiation therapy. Often, the urethral neoplasm does not invade the bladder. We treated 5 women with stage C urethral cancer by wide local excision with or without concomitant radiation therapy, while preserving the bladder. Local control was achieved in all patients with followup ranging from 4 to 75 months (median 42). We believe that bladder sparing treatment strategies should be considered for selected stage C tumors when the bladder is not invaded by the neoplasm.
膀胱切除术仍然是局部晚期（C期）尿道癌或放疗失败的A期或B期病变女性患者的标准治疗方法之一。通常，尿道肿瘤不会侵犯膀胱。我们对5例C期尿道癌女性患者进行了广泛局部切除，部分患者同时接受了放疗，同时保留了膀胱。所有患者均实现了局部控制，随访时间为4至75个月（中位时间42个月）。我们认为，当肿瘤未侵犯膀胱时，对于部分选定的C期肿瘤应考虑保留膀胱的治疗策略。
