Ampil F L
Obstet Gynecol. 1985 Dec;66(6):799-804.
This is a retrospective review of 11 cases of primary malignant neoplasm of the female urethra seen at the Louisiana State University Medical Center in Shreveport from 1951 to 1984. The disease was relatively more frequent in the 60- to 79-year age-group. Squamous cell carcinoma was the most common among the different observed histopathology. A modified clinical staging system is introduced. At diagnosis, eight of 11 subjects (73%) had locally extensive disease. The majority of the patients were treated with radiotherapy alone or in combination with surgery. The overall severe complication rate was low. The poor results (20% local control and survival) obtained in this small experience suggest that perhaps a study using promising adjuvant chemotherapeutic agents is warranted. A literature review summary of reported radiotherapy results is included.
这是一项对1951年至1984年在什里夫波特的路易斯安那州立大学医学中心所见的11例女性尿道原发性恶性肿瘤病例的回顾性研究。该疾病在60至79岁年龄组中相对更为常见。在观察到的不同组织病理学类型中，鳞状细胞癌最为常见。引入了一种改良的临床分期系统。在诊断时，11名受试者中有8名（73%）患有局部广泛性疾病。大多数患者接受了单纯放疗或放疗联合手术治疗。总体严重并发症发生率较低。这项小规模研究中获得的较差结果（20%的局部控制率和生存率）表明，或许有必要开展一项使用有前景的辅助化疗药物的研究。文中还包括了已报道放疗结果的文献综述总结。
