Okada M, Sakakibara Y, Suehiro K, Shichijou K, Toshida H, Oba O, Naito H, Takatori M, Kurasako T, Tada K
Department of Cardiovascular Surgery, Hiroshima City Hospital, Japan.
Kyobu Geka. 1993 Jul;46(8 Suppl):668-71.
How to optimize cerebral perfusion pressure and flow during selective extracorporeal circulation is a crucial problem for cerebral protection in surgical repair of aortic arch aneurysm. Among 47 cases of aortic arch replacement between 1980 and 1992, extracorporeal circulation (ECC) for the first 17 cases [group-1] were hypothermic ECC with selective cerebral perfusion (SCP) and 8 cases [group-2] with hypothermic ECC with hypothermic cardiac arrest. For the latest 16 cases [group-3] we introduced continuous O2 saturation monitoring by oximetry catheter placed in internal jugular bulb (SIJVO2) and maintained SIJVO2 value above 90% to effectively adjust pump flow to optimize cerebral perfusion pressure and flow for cerebral protection. We have retrospectively compared the effectiveness of SIJVO2 monitoring among these three groups. The mortality was 35% (6 cases: group-1), 37% (3 cases: group-2) and 6% (1 case: group-3) respectively. Cerebral dysfunction which were diagnosed in immediate postoperative period were 23% (4 cases: group-1), 0% (0 case: group-2) and 6% (1 case: group-3) respectively. We conclude continuous monitoring of SIJVO2 during selective ECC in aortic arch replacement is useful to optimize cerebral perfusion pressure and flow thereby reducing postoperative cerebral damage by selective ECC.
在主动脉弓动脉瘤手术修复中,如何在选择性体外循环期间优化脑灌注压和血流量是脑保护的关键问题。1980年至1992年间的47例主动脉弓置换病例中,前17例[第1组]的体外循环(ECC)采用低温ECC并选择性脑灌注(SCP),8例[第2组]采用低温ECC并低温心脏停搏。对于最近的16例[第3组],我们通过置于颈内静脉球部的血氧饱和度测定导管进行连续氧饱和度监测(SIJVO2),并将SIJVO2值维持在90%以上,以有效调整泵流量,优化脑灌注压和血流量以实现脑保护。我们回顾性比较了这三组中SIJVO2监测的有效性。死亡率分别为35%(6例:第1组)、37%(3例:第2组)和6%(1例:第3组)。术后即刻诊断出的脑功能障碍分别为23%(4例:第1组)、0%(0例:第2组)和6%(1例:第3组)。我们得出结论,在主动脉弓置换的选择性ECC期间连续监测SIJVO2有助于优化脑灌注压和血流量,从而减少选择性ECC引起的术后脑损伤。