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肢端肥大症患者腰椎和股骨的骨密度

[Bone density of the lumbar spine and femur in acromegaly].

作者信息

Hübsch P, Kotzmann H, Svoboda T, Kainberger F M, Bankier A, Seidl G

机构信息

Ludwig-Boltzmann-Institut für radiologisch-physikalische Tumordiagnostik, Universitätsklinik für Radiodiagnostik, Wien.

出版信息

Radiologe. 1993 Aug;33(8):457-61.

PMID:8372172
Abstract

Acromegaly is regarded as a cause for secondary osteoporosis, whereas recent papers suggest that growth hormone increases bone mineral density (BMD). In 16 patients with active acromegaly we found an increased BMD compared to normal controls in the lumbar spine and the proximal femur by means of dual energy X-ray absorptiometry. This increase in BMD was statistically significant in the femoral neck and in Ward's triangle (P = 0.05). Moreover, no signs of osteoporosis were found radiologically.

摘要

肢端肥大症被认为是继发性骨质疏松症的一个病因,然而近期的论文表明生长激素可增加骨矿物质密度(BMD)。我们通过双能X线吸收法发现,16例活动期肢端肥大症患者的腰椎和股骨近端的骨矿物质密度相较于正常对照组有所增加。股骨颈和沃德三角区的骨矿物质密度增加具有统计学意义(P = 0.05)。此外,影像学检查未发现骨质疏松的迹象。

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