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骨显像和镓-67显像在评估多发性骨髓瘤患者肋骨病变中的应用

Bone and 67Ga scintigraphy in the evaluation of rib lesions in patients with multiple myeloma.

作者信息

Otsuka N, Fukunaga M, Morita K, Ono S, Nagai K, Yamada O, Yawata Y

机构信息

Department of Nuclear Medicine, Kawasaki Medical School, Japan.

出版信息

Radiat Med. 1993 May-Jun;11(3):75-80.

PMID:8372240
Abstract

Rib lesions in 14 patients with multiple myeloma were evaluated by 99mTc-phosphorous compound bone scintigraphy and 67Ga scintigraphy. In the present study, in order to accurately detect rib lesions in multiple myeloma, bone and 67Ga scintigraphy were performed in 14 patients with multiple myeloma. The patterns of radionuclide accumulation in rib lesions on bone scintigraphy were classified by their grade, type, and site, and the findings were compared with the results of 67Ga scintigraphy. Thus, in cases of multiple myeloma, it was important to consider carefully both the intensity and the design of bone scintigraphy in combination with follow-up study by 67Ga scintigraphy. As a result of such consideration, we found that bone and 67Ga scintigraphy were useful in distinguishing invasive lesions from benign degenerative changes in the rib cage in cases with suspected rib involvement of multiple myeloma.

摘要

对14例多发性骨髓瘤患者的肋骨病变进行了99mTc-磷化合物骨闪烁显像和67Ga闪烁显像评估。在本研究中,为准确检测多发性骨髓瘤的肋骨病变,对14例多发性骨髓瘤患者进行了骨和67Ga闪烁显像。根据肋骨病变在骨闪烁显像上放射性核素聚集的程度、类型和部位对其进行分类,并将结果与67Ga闪烁显像的结果进行比较。因此,在多发性骨髓瘤病例中,结合67Ga闪烁显像的随访研究,仔细考虑骨闪烁显像的强度和设计非常重要。经过这样的考虑,我们发现骨和67Ga闪烁显像有助于在疑似多发性骨髓瘤累及肋骨的病例中区分肋骨侵袭性病变与良性退行性改变。

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