Rentería-Ibarra M, Frías-Márquez S G, Michel-Aceves R J, Navarrete-Arellano M
Servicio de Genética, Hospital Central Militar, México, D.F., México.
Bol Med Hosp Infant Mex. 1993 Sep;50(9):666-70.
The Fryns' syndrome is characterized by multiple congenital deformities such as cranio-facial anomalies, diaphragmatic hernia, pulmonary hypoplasia, distal anomalies of the extremities and diverse cardiovascular, digestive, urogenital and central nervous system malformations. Heredity trait is recessive-autosomic with variable expression. Mortality is the rule. Diagnosis must be suggested by early polyhydramnios, premature delivery, familial tendency and perinatal mortality. In the present paper, a case with the most significant features and with other features not previously described is reported.
