Sievers K W, Feldmann H J, Füller J, Molls M, Sack H
Röntgendiagnostisches Zentralinstitut, Universitätsklinikum Essen.
Rofo. 1993 Sep;159(3):245-50. doi: 10.1055/s-2008-1032758.
For the purpose of assessing perfusion of deep seated pelvic tumours 22 dynamic MR studies were carried out and correlated with relevant CT studies as well as with the intratumoural distribution of temperature under hyperthermia in different areas. Using changes of signal intensity, dynamic MR could thus distinguish between well and poorly perfused tumours, besides supplying reliable information on inhomogeneities in tumour perfusion. Altogether, a correlation of 0.92 (p < 0.001) was found between MR and CT and 0.72 (p < 0.001) between MR and the steady state determination of intratumoural temperature. Thus, dynamic MR provides prognostic information concerning therapeutic temperatures (> = 42 degrees C) in tumours and therefore their response to hyperthermia.
为评估深部盆腔肿瘤的灌注情况，进行了22项动态磁共振研究，并与相关的CT研究以及不同区域热疗时肿瘤内温度分布进行了关联。利用信号强度的变化，动态磁共振不仅可以区分灌注良好和灌注不良的肿瘤，还能提供有关肿瘤灌注不均匀性的可靠信息。总体而言，磁共振与CT之间的相关性为0.92（p < 0.001），磁共振与肿瘤内温度稳态测定之间的相关性为0.72（p < 0.001）。因此，动态磁共振可提供有关肿瘤治疗温度（>= 42摄氏度）及其对热疗反应的预后信息。
