Wiegerinck M A, Van Dop P A, Brosens I A
Department of Obstetrics and Gynecology, St. Joseph Hospital, Veldhoven, The Netherlands.
Fertil Steril. 1993 Sep;60(3):461-4. doi: 10.1016/s0015-0282(16)56161-5.
To evaluate changes in peritoneal endometriosis by the type of lesion in comparison with the scoring system of the revised American Fertility Society (AFS) classification.
Prospective evaluation at laparoscopy before and 6 months after discontinuance of a 3-month medical therapy with either dydrogesterone or danazol.
A general hospital.
Forty cycling women with endometriosis and infertility. Fourteen patients could be fully evaluated by their revised AFS score and type of peritoneal lesion.
Laparoscopy before and 6 months after discontinuance of medical therapy.
Revised AFS score and type of peritoneal lesions.
The revised AFS score decreased or remained unchanged in 13 of 14 patients, whereas red papular or vesicular lesions were present at both laparoscopies in 5, absent in 4, disappeared in 3, and appeared de novo in 2. A changing pattern also was seen in other types of small peritoneal lesions.
In contrast with the revised AFS score, the study of the type of peritoneal lesions shows a changing pattern of activity. The significance in pathophysiological and clinical studies should be investigated further.
通过病变类型评估腹膜子宫内膜异位症的变化,并与修订后的美国生育协会(AFS)分类评分系统进行比较。
在停用炔诺孕酮或达那唑进行3个月药物治疗前及治疗后6个月进行腹腔镜检查的前瞻性评估。
一家综合医院。
40名患有子宫内膜异位症和不孕症的育龄妇女。14名患者可根据其修订后的AFS评分和腹膜病变类型进行全面评估。
药物治疗前及停药后6个月进行腹腔镜检查。
修订后的AFS评分和腹膜病变类型。
14例患者中13例的修订后AFS评分降低或保持不变,而5例患者在两次腹腔镜检查时均出现红色丘疹或水疱样病变,4例未出现,3例消失,2例新发。其他类型的小腹膜病变也呈现出变化模式。
与修订后的AFS评分不同,腹膜病变类型研究显示出活动的变化模式。其在病理生理学和临床研究中的意义应进一步研究。