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绝经后出血女性子宫内膜的经阴道扫描与细胞学和组织学的比较

Endovaginal scanning of the endometrium compared to cytology and histology in women with postmenopausal bleeding.

作者信息

Karlsson B, Granberg S, Wikland M, Ryd W, Norström A

机构信息

Department of Obstetrics and Gynecology, Sahlgrenska Hospital, Göteborg, Sweden.

出版信息

Gynecol Oncol. 1993 Aug;50(2):173-8. doi: 10.1006/gyno.1993.1188.

DOI:10.1006/gyno.1993.1188
PMID:8375731
Abstract

Endovaginal scanning (EVS) of the endometrium has recently been proposed as a method for the investigation of the endometrial mucosa. In this study, the specificity and sensitivity of EVS have been compared with endometrial cytology and D&C to discriminate between a normal and pathological endometrium. The study included 105 women who underwent preoperative endovaginal ultrasound investigation, endometrial cytology, and D&C because of postmenopausal bleeding. A specificity of 81% and a sensitivity of 97% in diagnosing morphological alterations by means of endovaginal ultrasound was found. The corresponding figures for cytological evaluation were 81 and 58%, respectively. We conclude that endovaginal ultrasound is a valuable diagnostic instrument for detecting pathological conditions in the uterine mucosa and as sensitive as endometrial cytology or D&C.

摘要

近期有人提出经阴道扫描(EVS)子宫内膜可作为一种研究子宫内膜黏膜的方法。在本研究中,已将EVS的特异性和敏感性与子宫内膜细胞学及刮宫术进行比较,以鉴别正常与病理性子宫内膜。该研究纳入了105名因绝经后出血而接受术前经阴道超声检查、子宫内膜细胞学检查及刮宫术的女性。结果发现,经阴道超声诊断形态学改变的特异性为81%,敏感性为97%。细胞学评估的相应数字分别为81%和58%。我们得出结论,经阴道超声是检测子宫黏膜病理状况的一种有价值的诊断工具,其敏感性与子宫内膜细胞学或刮宫术相当。

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Gynecol Oncol. 1993 Aug;50(2):173-8. doi: 10.1006/gyno.1993.1188.
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引用本文的文献

1
Clinical evaluation of women with PMB. Is it always necessary an endometrial biopsy to be performed? A review of the literature.经阴道超声检查在子宫内膜息肉诊断中的应用价值 目的:探讨经阴道超声检查(TVS)在子宫内膜息肉(EMPs)诊断中的应用价值。 方法:回顾性分析 2016 年 1 月至 2019 年 12 月在我院就诊的经宫腔镜检查和病理证实的 90 例 EMPs 患者的临床资料,所有患者术前均行 TVS 检查,以宫腔镜检查及病理结果为金标准,计算 TVS 检查诊断 EMPs 的灵敏度、特异度、阳性预测值、阴性预测值及准确性,并分析 TVS 对息肉大小、数目、位置、内部回声及血流情况的诊断价值。 结果:宫腔镜检查及病理诊断为 90 例 EMPs,单发 62 例(68.9%),多发 28 例(31.1%);息肉直径 0.5~2.5cm,平均(1.12±0.51)cm。TVS 检查诊断 EMPs 的灵敏度、特异度、阳性预测值、阴性预测值及准确性分别为 97.8%(88/90)、91.1%(82/90)、96.7%(88/91)、94.4%(82/87)、95.6%(170/178)。TVS 诊断 EMPs 的大小与病理结果呈正相关(r=0.834,P<0.001)。单发息肉与多发息肉在形态、内部回声及血流分布方面比较,差异均有统计学意义(P<0.05)。 结论:TVS 检查诊断 EMPs 具有较高的灵敏度、特异度、准确性,可作为 EMPs 的首选筛查方法。
Arch Gynecol Obstet. 2011 Feb;283(2):261-6. doi: 10.1007/s00404-010-1601-3. Epub 2010 Aug 4.
2
Hysteroscopy as a standard procedure for assessing endometrial lesions among postmenopausal women.宫腔镜检查作为绝经后女性子宫内膜病变评估的标准程序。
Sao Paulo Med J. 2007 Nov 1;125(6):338-42. doi: 10.1590/s1516-31802007000600007.
3
Bias associated with delayed verification in test accuracy studies: accuracy of tests for endometrial hyperplasia may be much higher than we think!检验准确性研究中与延迟验证相关的偏倚:子宫内膜增生检测的准确性可能比我们想象的要高得多!
BMC Med. 2004 May 11;2:18. doi: 10.1186/1741-7015-2-18.
4
Endometrial sampling and general practice.子宫内膜取样与全科医疗
Br J Gen Pract. 1997 Jun;47(419):387-91.