Richter A, Beideck S, Bender W, Frosch P J
Hautklinik der Städtischen Kliniken Dortmund.
Hautarzt. 1993 Aug;44(8):521-3.
A 66-year-old man was treated with cyclosporin A (Sandimmun) after a kidney transplant and developed numerous epidermal cysts, comedones and folliculitis in the 2nd year of the immunosuppressive therapy. The eruptions were more marked on the back and in the temporal and retroauricular regions of the face. Histological examination of a cystic tumour revealed a follicular cyst of the acro-infundibular type. While hypertrichosis and gingival hyperplasia are now well known as side effects of cyclosporin A, cystic and acneiform skin lesions must also be attributed to this drug.
一名66岁男性在肾移植后接受环孢素A(山地明)治疗,在免疫抑制治疗的第2年出现了大量表皮囊肿、粉刺和毛囊炎。皮疹在背部以及面部颞部和耳后区域更为明显。对一个囊性肿瘤进行组织学检查发现是顶泌汗腺漏斗型毛囊囊肿。虽然多毛症和牙龈增生现在已被公认为环孢素A的副作用,但囊性和痤疮样皮肤损害也必须归因于这种药物。