Strahan Jamison E, Burch Joanna M
Department of Dermatology, The Children's Hospital, Aurora, CO 80045, USA.
Arch Dermatol. 2009 Jul;145(7):797-9. doi: 10.1001/archdermatol.2009.98.
In adult organ transplant recipients, nodulocystic acne induced by the use of cyclosporine can be treated successfully with isotretinoin. Cyclosporine's acnegenic effects in children and the pediatric response to treatment are less clear.
A 9-month-old boy presented with cysts and nodules on his face after he began cyclosporine therapy after a heart transplantation. We describe successful treatment with cessation of cyclosporine therapy and administration of isotretinoin.
Nodulocystic acne may be induced by the use of cyclosporine in children as well as adults. When it occurs, it can be managed with cessation of cyclosporine therapy and treatment with isotretinoin. Because this management approach may influence other outcomes in children with transplants, it is best to treat these patients using a multidisciplinary approach.
在成年器官移植受者中，使用环孢素引起的结节囊肿性痤疮可用异维A酸成功治疗。环孢素在儿童中的致痤疮作用以及儿科对治疗的反应尚不清楚。
一名9个月大的男孩在心脏移植后开始使用环孢素治疗后，面部出现囊肿和结节。我们描述了通过停用环孢素治疗并给予异维A酸成功治疗的情况。
儿童和成人使用环孢素都可能诱发结节囊肿性痤疮。当出现这种情况时，可通过停用环孢素治疗并用异维A酸进行治疗。由于这种管理方法可能会影响移植儿童的其他结局，因此最好采用多学科方法治疗这些患者。
