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乙型病毒与丙型病毒感染后慢性活动性肝炎患者的血浆纤维连接蛋白及血清补体C3水平

Plasma fibronectin and serum complement C3 levels in chronic active hepatitis following virus "B" versus virus "C" infection.

作者信息

Abdel Rahman M M, el Nasr M S, Mahmoud S A, Soliman A, Salama M M

机构信息

Department of Tropical Medicine, Faculty of Medicine, Al-Azhar University, Cairo.

出版信息

J Egypt Soc Parasitol. 1993 Aug;23(2):579-89.

PMID:8376876
Abstract

Plasma fibronectin and serum complement C3 levels were estimated in 30 patients with chronic active hepatitis (CAH) post virus "B" and another 30 patients with CAH post virus "C" as well as 20 normal healthy subjects. Fibronectin level was significantly increased in CAH when compared to normal controls. Moreover, fibronectin level was significantly increased in CAH following virus "C" when compared to CAH following virus "B" hepatitis. Concerning complement C3 there was no significant changes in the different groups studied. We may conclude that CAH following virus "C" may lead to vigorous inflammatory damage than CAH following virus "B" infection.

摘要

对30例乙型病毒感染后慢性活动性肝炎(CAH)患者、30例丙型病毒感染后CAH患者以及20名正常健康受试者的血浆纤维连接蛋白和血清补体C3水平进行了评估。与正常对照组相比,CAH患者的纤维连接蛋白水平显著升高。此外,与乙型肝炎病毒感染后的CAH相比,丙型肝炎病毒感染后的CAH患者纤维连接蛋白水平显著升高。关于补体C3,在所研究的不同组中没有显著变化。我们可以得出结论,丙型肝炎病毒感染后的CAH可能比乙型肝炎病毒感染后的CAH导致更剧烈的炎症损伤。

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